2010 Football Schedule
| Date | Opponent | Time / Notes |
| August 28 | Central Missouri | 6:00 PM |
| September 4 | at Truman State | 7:00 PM |
| September 11 | Bacone College | 1:30 PM |
| September 18 | William Jewell | 1:30 PM |
| September 25 | at Southern Nazarene | 6:00 PM |
| October 2 | at Urbana | 12:00 PM |
| October 9 | at Lincoln | 2:00 PM |
| October 23 | *Central State (homecoming) | 2:00 PM |
| October 30 | Saint Joseph's College | 1:30 PM |
| November 6 | at Southeast Missouri (FCS) | 1:00 PM |
| November 13 | at Arkansas Tech | 2:00 PM |
| November 20 | NCAA DII Playoffs Round 1 | |
| November 27 | NCAA DII Playoffs Round 2 | |
| December 4 | NCAA DII Quarter-Finals | |
| December 11 | NCAA DII Semi-Finals | |
| December 18 | NCAA DII Championship |
* Homecoming Game